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Descriptions
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The National
Synchrotron Light Source at Brookhaven National Laboratory includes a
Department of Energy (DOE) supported x-ray beam line extensively used
by structural biologists studying virus structure, including the structure
of HIV.
In addition,
through its National Laboratory system, DOE provides user facilities at
other synchrotron light sources and at neutron beam facilities, which
can be used by researchers to characterize the structural configuration
of intact HIV, and HIV's biochemical components, often in complexes with
inhibitors. These studies assist in the development of novel therapies,
as well as advance our understanding of the pathogenesis and fundamental
biology of HIV growth.
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